Haploidentical bone marrow transplant is a type of stem cell transplant that involves using stem cells from a donor who is a half-match for the recipient. In a haploidentical transplant, the donor is typically a family member, such as a parent, child, or sibling, who shares only half of the recipient's human leukocyte antigen (HLA) tissue type.
HLA markers are proteins on the surface of cells that are used to identify the body's own cells and tissues from foreign cells and tissues. The closer the HLA match between the donor and recipient, the lower the risk of graft-versus-host disease (GVHD), a common complication of allogeneic stem cell transplants in which the donor's immune cells attack the recipient's body.
In a haploidentical transplant, the donor's stem cells are collected and then treated to remove T-cells, which are the immune cells that can cause GVHD. This process is called T-cell depletion, and it reduces the risk of GVHD in the recipient.
After T-cell depletion, the donor's stem cells are infused into the recipient's bloodstream, where they travel to the bone marrow and begin to create new blood cells. The recipient will receive high-dose chemotherapy or radiation therapy prior to the transplant to destroy any remaining cancer cells and make room for the donor's stem cells.
At Sterling Hospitals Ahmedabad, we offer haploidentical bone marrow transplants as a treatment option for patients with blood disorders, such as leukemia, lymphoma, and other conditions. Our transplant team includes experienced hematologists, oncologists, and other specialists who work together to provide comprehensive care throughout the transplant process.
We use the latest technology and techniques to ensure the best possible outcomes for our patients, and we offer a range of support services to help patients and their families during this challenging time. Our team includes social workers, nutritionists, and other professionals who can provide guidance and support throughout the transplant process.
If you or a loved one has been diagnosed with a blood disorder that may require a haploidentical bone marrow transplant, our team at Sterling Hospitals Ahmedabad is here to help. We are committed to providing compassionate, personalized care to each of our patients, and to working together to achieve the best possible outcomes.